Temonix 100 Mg (Temozolomide)

Description

Temonix 100 mg contains Temozolomide, a chemotherapy drug that’s largely used to treat brain excrescences of certain types similar as glioblastoma multiforme and anaplastic astrocytoma. Temozolomide belongs to a new class of specifics known as alkylating agents, which work by killing the DNA of cancer cells, ultimately halting them from dividing and adding in number. The drug is generally administered as part of a total cancer remedy authority that may include surgery and radiotherapy.

Composition and Form

The active component of every capsule of Temonix 100 mg is Temozolomide 100 mg. It’s in the form of a capsule for oral administration and generally in capsule form. The capsules are especially designed to grease ease of immersion and constant delivery of the medicine into the blood force, hence effective to kill cancer cells.

Mechanism of Action

Temozolomide, the medicine in Temonix, is an alkylating agent. Upon administration into the body, it gets chemically converted to its active metabolite — MTIC (monomethyl triazeno imidazole carboxamide). The active metabolite of temozolomide combines with the DNA of cancer cells by attaching methyl groups to specific spots on the DNA patch. Because of this exertion, the cancer cells are deprived of their capability to divide and repair, leading to cell cycle arrest and ultimately cell death.
This authority is especially effective in treating presto- growing excrescences like glioblastoma multiforme, a veritably aggressive and resistant excrescence to numerous other chemotherapy medicines.

Therapeutic Uses

Temonix 100 mg is used for the treatment of:

First- time opinion of glioblastoma multiforme (GBM)
It’s administered in combination with radiation remedy, also the conservation phase using Temonix monotherapy to ameliorate the survival of cases and time to excrescence progression.
Refractory or intermittent anaplastic astrocytoma
In cases of excrescence rush or failure to respond to being treatments, Temonix offers a possible alternate- line treatment because it can cross the blood- brain hedge.
In some clinical conditions, oncologists may turn to Temonix for other types of malice under off- marker use, but this will be dependent on individual case conditions and is conducted under close medical regulation.

Dosage and Administration

The cure of Temonix 100 mg is variable ground on factors like excrescence type. Body face area (BSA), response to remedy, and forbearance to side effects.
For primary remedy of glioblastoma, Temonix is administered at 75 mg/ m ² daily during radiation remedy for 42 days follow by conservation when it’s taken for 5 days out of every 28-day cycle.
For intermittent anaplastic astrocytoma, 150 – 200 mg/ m ² per day on a 28-day schedule for 5 days is recommend.

It should be take on an empty stomach, rather at least one hour after or before food, with a full glass of water. Capsules should be swallowed whole — do not open, crush, or bite them.

Because of the implicit difficulty of dosing and toxin, Temonix should always be administere under close medical supervision.

Side Effects

Like all chemotherapy agents, Temonix may beget side effects, but these aren’t set up in everyone. Side effects most generally observe are

Nausea and puking

Weakness and fatigue

Loss of appetite

Headache

Constipation or diarrhea

Hair loss (alopecia)

Anemia, neutropenia, and thrombocytopenia (drop in blood cell counts)

Severe side effects can be

Low white blood cell count infection

Low platelet count bleeding or bruising

Abnormal liver function

Antipathetic responses (lump, itching, or rash)

Regular blood tests are need ahead and during remedy to cover the counts of blood cells and the function of organs. New or changing symptoms should be report to the healthcare provider at formerly.

Precautions and Warnings

Gestation and lactation are contraindicate while entering Temonix, as it may beget detriment to the fetus. Women of travail age must use effective contraception during and at least six months following the last dose of treatment. Men also must avoid gestation during and for three months after the end of treatment.

threat of infection Because Temonix can suppress bone gist function, cases may be more at threat for infection. Effective hygiene and avoiding contact with infected individualities are pivotal.

Liver or order impairment It may be necessary to reduce the lozenge in cases with being organ impairment.

Vaccines: Live vaccines should be avoid during treatment since the vulnerable system is suppress.

Drug Interactions

Temonix will be anticipat to interact with certain medicines, similar as

Anticonvulsants (e.g., phenytoin, valproic acid)

Steroids (e.g., dexamethasone)

Other cytotoxic medicines

Antiemetics and antibiotics

All medicines and supplements inform to the doctor by cases so that dangerous relations are avert.

Storage and Handling

Place Temonix 100 mg capsules at room temperature, not exceeding 25 °C, in a dry terrain, defended from sun.

Store beyond reach of children and faves.

Caregivers should clean their hands both before and after touching the capsules, and shouldn’t open or crush the capsules.

Conclusion

Temonix 100 mg (Temozolomide) is a well- proven, effective oral chemotherapeutic agent that plays a particularly vital part in the treatment of largely aggressive brain cancers like glioblastoma multiforme and anaplastic astrocytoma. The capability to cross the blood- brain hedge places it in a unique position among the most effective agents to treat brain cancers. Side effects, while possible, are reduce by watchful monitoring under the watch of a doctor and with probative care similar that the treatment permitted by utmost cases.
lass=”yoast-text-mark” />>For resistant brain excrescence cases, Temonix offers an active and hopeful choice that can extend survival, slacken excrescence growth, and ameliorate overall quality of life when administered within the frame of a duly designed cancer treatment program.